Some substituted Dibenzo (b, e) azepin - diones were synthesized from 4 - amino acetyl chloride and 2 -amino benzoic acid by total organic synthesis involving three intermediate. All the eights compounds of the series were characterized by spectral data and evaluated against antibacterial and antifungal activity by Agar plate disc diffusion method. The results indicated that the lactum intermediate exhibited comparable antibacterial activity than rest of the compounds whilst others showed good antifungal activity with diminished antibacterial property.
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